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September 27, 2019 7 min read

T is most often associated with sex drive and plays a role in sperm production. It affects everything from your mood to bone and muscle mass to the way men store body fat and even red blood cell production. 

It's in every man's best interest to optimize your body's ability to produce it as long as you possibly can, and the combination of a healthy diet, strength training, and proper supplementation such as ALPHA-AF can do just that. 

Benefits of ALPHA-AF:

  • Promotes testosterone
  • Enhances male libido
  • Improves the ability to adapt to stress
  • Improves sleep
  • Enhances fat breakdown
  • Neutralizes inflammation
  • Anti-Estrogen

Key ingredients in Alpha-AF and what they do:

Vitamin D3 (as cholecalciferol)

Vitamin D is a fat-soluble nutrient and one of the 24 micronutrients critical for human survival. The sun is the major natural source of the nutrient, but vitamin D is also found naturally in fish and eggs. It is also added to dairy products.

Supplemental vitamin D is associated with a wide range of benefits, including increased cognition, immune health, bone health, and well-being.

Supplementation can also reduce the risks of cancer, heart disease, diabetes, and multiple sclerosis. People deficient in vitamin D may also experience increased testosterone levels after supplementation.

Vitamin D needs to undergo two conversion steps to become active. 

First, it is converted to calcidiol, or 25(OH)D, in your liver. This is the storage form of the vitamin. Second, it is converted to calcitriol, or 1,25(OH)2D, mostly in your kidneys. This is the active, steroid-hormone form of vitamin D. Calcitriol interacts with the vitamin D receptor (VDR), which is found in almost every single cell in your body. 

When the active form of vitamin D binds to this receptor, it turns genes on or off, leading to changes in your cells. This is similar to how most other steroid hormones work. 

Vitamin D affects various cells related to bone health. For example, it promotes the absorption of calcium and phosphorus from your gut. But scientists have recently discovered that it also plays roles in other areas of health, such as immune function and protection against cancer. 

An increase in testosterone has been noted in men with 3,332 IU of Vitamin D over the course of a year.

Additional potential benefits of Vitamin D:

  • Reduced risk of osteoporosis, falls, and fractures. Higher doses of vitamin D can help prevent osteoporosis, falls, and fractures in older adults.
  • Better strength. Vitamin D can increase physical strength in both upper and lower limbs.
  • Cancer prevention. Vitamin D may help prevent cancer. One study noted that 1,100 IU per day — alongside calcium — reduced cancer risk by 60%.
  • Depression management. Studies show that vitamin D may ease symptoms in people with clinical depression.
  • Reduced risk of type 1 diabetes. One study in infants linked 2,000 IU of vitamin D per day to a 78% reduced risk of type 1 diabetes.
  • Improved mortality. Some studies suggest that vitamin D reduces people's risk of dying during the study periods, indicating that it may help you live longer.

Byroviron (Bryonia Lacionosa)

Bryonia Laciniosa is an Ayurvedic herb used traditionally as an aphrodisiac and pro-fertility compound, touted to increase masculinity and enhance youthfulness during aging. 

It works by increasing Luteinizing Hormone (LH), Follicle-Stimulating Hormone (FSH) and Testosterone. The mechanism of action is hypothesized to be through hypothalamic stimulation, due to the above three hormones all increasing.

Key points to note:
  • Bryonia laciniosa is an herb used in Ayurvedic Medicine traditionally as a sexuality enhancer
  • The ethanolic extract of the seeds appears to be a potential testosterone enhancer.
  • An increase in sex organ weight of male rats has been noted alongside pro-libido effects, suggesting that testosterone plays a role
  • Enhances male libido and fertility

Fig: Effect of ethanolic extract on serum hormones level (FSH, follicle-stimulating hormones; LH, luteinizing hormones). The serum testosterone, luteinizing hormone, and follicular stimulating hormone was significantly increased in all the treated groups. Int J Impot Res. 2010 May-Jun;22(3):190-5


Safed Musli (50% saponins)

Safed Musli (chlorophytum borivilianum) is a rare herb long used in traditional Indian medicine as an aphrodisiac and adaptogen (a botanical that improves the body’s ability to adapt to stress whether physical, chemical or biological. 

Research shows that Safed Musli improves serum testosterone, sperm count and sperm motility.  It also has been shown to relieve stress.  Research also demonstrates that all parameters of sleep were improved in controlled research studies.

Magnesium (as Magnesium Aspartate)

Magnesium is the fourth most abundant mineral in your body, and your body can’t work properly without it.  About 60% of the magnesium in your body is found in bone, while the rest is in muscles, soft tissues, and fluids, including blood. 

In fact, every cell in your body contains it and needs it to function. One of magnesium's main roles is acting as a cofactor or "helper molecule" in the biochemical reactions continuously performed by enzymes. 

It’s involved in more than 600 reactions in your body, including:

  • Energy creation: Helps convert food into energy.
  • Protein formation: Helps create new proteins from amino acids.
  • Gene maintenance: Helps create and repair DNA and RNA.
  • Muscle movements: Is part of the contraction and relaxation of muscles.
  • Nervous system regulation: Helps regulate neurotransmitters, which send messages throughout your brain and nervous system.

Zinc

Zinc is considered an essential nutrient, meaning that your body can’t produce or store it. It is the second-most-abundant trace mineral in your body and is present in every cell so you need to get a constant supply through diet or supplementation. 

Zinc is required for numerous processes in your body, including gene expression, enzymatic reactions, immune function, protein synthesis, DNA synthesis, wound healing, and growth and development. The main mechanism of action for zinc is that it enables the male body to produce testosterone.

Zinc not only impacts the level of testosterone but may cause a loss of the ability to detect subtle chemicals that induce arousal. Therefore, your levels of zinc may affect erectile dysfunction.

Zinc Glycinate is used in ALPHA-AF as it is more effective for hormonal modulating effects when zinc is bound to glycine.

DHEA

DHEA is a naturally occurring hormone and either exerts benefits on its own, or can convert into testosterone depending on the body's need. DHEA supplementation is potent for reducing the 'effects of aging. 

Its effects are driven by the actions of testosterone after this conversion occurs, as well as the DHEA molecule itself. DHEA decreases with age and it’s estimated up to 80% decrease throughout adulthood. Levels begin to decrease around age 30.

Research demonstrates that acute supplementation of DHEA prior to exercise is able to promote levels of free testosterone independent of changes in testosterone in middle-aged men and prevent a decline of free testosterone during exercise. Research also shows that DHEA may increase libido and sexual function.

Fig: Total testosterone response after an acute bout of high-intensity interval training (HIIT) for middle-aged and young control men during DHEA and placebo trials

Figure: Free testosterone response after an acute bout of high-intensity interval training (HIIT) for middle-aged and young control men during DHEA and placebo trials

Vitamin B6 (as pyridoxine Hcl)

Vitamin B6, also known as pyridoxine, is a water-soluble vitamin that your body needs for several functions. Your body cannot produce vitamin B6, so you must obtain it from foods or supplements.

It’s significant to protein, fat and carbohydrate metabolism and the creation of red blood cells and neurotransmitters. Consuming adequate amounts of vitamin B6 is important for optimal health and may even prevent and treat chronic diseases.

Here are 9 health benefits of vitamin B6, backed by science:

  1. May improve mood and reduce symptoms of depression
  2. May promote brain health and reduce Alzheimer’s risk
  3. May prevent and treat anemia by aiding hemoglobin production
  4. May be useful in treating symptoms of PMS
  5. May help treat nausea during pregnancy
  6. May prevent clogged arteries and reduce heart disease risk
  7. May help prevent cancer
  8. May promote eye health and prevent eye diseases
  9. May treat inflammation associated with Rheumatoid arthritis

BioperineTM (Black Pepper Fruit Extract)

Bioperine is the active ingredient in black pepper that contributes to that unique spice you taste. Black pepper has long been regarded as beneficial to one’s health throughout history.

Now with the help of modern science and clinical research, more Piperine benefits are being discovered. Here are just several of those science-backed health benefits of black pepper extract. 

  • High in antioxidants: Black pepper is rich in a potent antioxidant called piperine, which may help prevent free radical damage to your cells.
  • Has anti-inflammatory properties: Chronic inflammation may be an underlying factor in many conditions, such as arthritis, heart disease, diabetes, and cancer. Many laboratory studies suggest that piperine — the main active compound in black pepper — may effectively fight inflammation.
  • May benefit your brain: Piperine has been shown to improve brain function in animal studies. In particular, it has demonstrated potential benefits for symptoms related to degenerative brain conditions like Alzheimer’s and Parkinson’s disease.
  • May have cancer-fighting properties: Black pepper contains an active compound that has slowed the replication of cancer cells and induced cancer cell death in test-tube studies. However, these effects have not been studied in people.
  • Boosts absorption of nutrients: Black pepper may increase the absorption of essential nutrients like calcium and selenium, as well some beneficial plant compounds, such as those found in green tea and turmeric.

Fig: Effect of piperine on the production of proinflammatory mediators.  Higher levels of piperine significantly reduced pro-inflammatory mediators

ALPHA-AF promotes natural T while acting as anti E (love handles and gyno) and it's one of the best products for PCT after using STEEL Andros.

It's in every man's best interest to optimize your body's ability to produce T as long as you possibly can, and the combination of a healthy diet, strength training, and proper supplementation such as ALPHA-AF can do just that!

References

Vitamin D References:

  • Am J Clin Nutr. 2008 Aug;88(2):491S-499S
  • J Steroid Biochem Mol Biol. 2011 Jul;125(3-5):159-68.
  • PLoS One. 2013;8(3):e58725.
  • Ann N Y Acad Sci. 1980;355:1-17.
  • Horm Metab Res. 2011 Mar;43(3):223-5
  • Curr Med Res Opin. 2013 Apr;29(4):305-13
  • J Sci Med Sport. 2015 Sep;18(5):575-80

Bryonia Lacionosa References:

  • Int J Impot Res. 2010 May-Jun;22(3):190-5.

Safed Musli References:

  • Ayu. 2013 Jul;34(3):273-5. doi: 10.4103/0974-8520.123118.
  • Pharmacologyonline 1: 320-328 (2009)
  • Indian J Exp Biol. 2007 Nov;45(11):974-9.
  • Integr Med Insights. 2012;7:7-14

Magnesium References:

  • Nutrients. 2015 Sep 23;7(9):8199-226.
  • Physiol Rev. 2015 Jan;95(1):1-46

Zinc References:

  • Nutrients. 2013 Aug; 5(8): 3184–3211.
  • J Hum Reprod Sci. 2009 Jul-Dec; 2(2): 57–61

DHEA References:

  • Physiol Res. 2003;52(4):397-407
  • Curr Opin Endocrinol Diabetes Obes. 2010 Jun;17(3):217-23.
  • Best Pract Res Clin Endocrinol Metab. 2004 Sep;18(3):363-80.
  • Urology. 1999 Mar;53(3):590-4
  • Eur J Appl Physiol. 2013 Jul;113(7):1783-92.

Vitamin B6 References:

  • National Institutes of Health: Office of Dietary Supplements
  • Molecules.  2010 Jan 20;15(1):442-59
  • Psychother Psychosom 2004 Nov-Dec;73(6): 340-3

BioperineTM (Black Pepper Fruit Extract) References:

  • Redox Rep. 2004;9(2):105-10
  • J Transl Med. 2018 Jan 25;16(1):14
  • J Clin Diagn Res. 2015 Apr;9(4):FF01-4
  • Crit Rev Food Sci Nutr. 2013;53(9):875-86
  • Mol Neurobiol. 2011 Oct;44(2):142-59
  • Nutrients. 2016 Aug 12;8(8)
  • Arthritis Res Ther. 2009;11(2):R49.

 

Dr. Paul Henning, PhD

About Dr. Paul

I'm currently an Army officer on active duty with over 15 years of experience and also run my own health and wellness business. The majority of my career in the military has focused on enhancing Warfighter health and performance. I am passionate about helping people enhance all aspects of their lives through health and wellness. Learn more about me