If you're looking for a way to boost your cognitive function and improve your focus and memory, look no further than FOCUSED-AF.
FOCUSED-AF combines the unique characteristics of several high-grade nootropics, creating a synergistic effect to help optimize your cognitive abilities and help you perform at your best.
Vitamin B6, also known as pyridoxine, is a water-soluble vitamin that your body needs for several functions. It’s significant to protein, fat and carbohydrate metabolism and the creation of red blood cells and neurotransmitters. Your body cannot produce vitamin B6, so you must obtain it from foods or supplements. Consuming adequate amounts of vitamin B6 is important for optimal health and may even prevent and treat chronic diseases.
Here are 9 health benefits of vitamin B6, backed by science:
Vitamin B12, also known as cobalamin, is an essential vitamin that your body needs but cannot produce. It’s found naturally in animal products, but also added to certain foods and available as an oral supplement or injection. Vitamin B12 has many roles in your body. It supports the normal function of your nerve cells and is needed for red blood cell formation and DNA synthesis. Vitamin B12 may benefit your body in impressive ways, such as by boosting your energy, improving your memory and helping prevent heart disease.
Here are 9 health benefits of vitamin B12, all based on science.
(Food Nutr Bull. 2008 Jun;29(2 Suppl):S101-11; discussion S112-5)
A natural choline compound found in the brain and one of the most bioavailable forms of choline. It is known to enhance a chemical in the brain called acetylcholine which is crucial for memory and learning functions. Alpha GPC can support cognitive health, improve memory, and learning, and it also acts as a neuroprotective agent. The main mechanism of action is by increasing acetylcholine and dopamine in the brain which is known to significantly enhance brain function. (Clin Ther. 2003 Jan;25(1):178-93)
Bacopa monnieri has been used by Ayurvedic medical practitioners for centuries for a variety of purposes, including improving memory and reducing anxiety. Research indicates it may boost brain function and alleviate anxiety and stress, among other benefits. A class of powerful compounds called bacosides in Bacopa monnieri is believed to be responsible for these benefits.
Below are seven emerging benefits of Bacopa monnieri:
(J Altern Complement Med. 2008 Jul; 14(6): 707–713)
Out of more than 600 carotenoids found in nature, the three macular carotenoids—lutein, RR-zeaxanthin, and RS (meso)-zeaxanthin—have garnered considerable attention for their role in preserving healthy vision. There is a growing agreement that macular carotenoids are conditionally essential nutrients, which is to say that under certain circumstances, supplementation may be required. Poor dietary intake increased blue light exposure, and current lifestyle changes are driving a greater need to supplement with these important nutrients to ensure adequate levels throughout life.
In addition to the health benefits to vision, the macular carotenoids within Lutemax 2020 are beneficial for:
Fig: Change in scores at 6 months in placebo vs. combined supplement groups (MXan), for five parameters of cognitive performance. Data points are means +/− standard deviations. Asterisks indicate statistical significance ( p < .05).
(N.T. Stringham, P.V. Holmes, J.M. Stringham, Physiol. Behav. 211 (2019).)
Natural caffeine is the type of caffeine that is naturally found in foods like coffee, tea, and chocolate. It works by blocking adenosine receptors in your brain.
Adenosine is a neurotransmitter that relaxes your brain, making you feel tired. By blocking adenosine receptors, caffeine prevents adenosine from binding to them. This keeps your brain from realizing that it’s tired, which is why caffeine is so effective at fighting off sleepiness and helping you remain more alert.
Even though natural and synthetic caffeine have the same bodily effects, here are a couple benefits of natural caffeine:
(Justin Evans, John R. Richards, Amanda S. Battisti; Caffeine StatPearls)
Mucuna is a tropical legume that’s very rich in L-Dopa—L-Dopa is the precursor to dopamine, norepinephrine, and epinephrine. It can promote healthy neurotransmission function and enhance your mood and immune system. The mechanism of action for mucuna is by increasing dopamine in the brain. This brain chemical (or neurotransmitter) is responsible for modulating several cognitive functions including mood, hand-eye-coordination, and others.
Mucuna can be a powerful tool to improve memory and cognitive abilities. Research indicates that L-DOPA was able to prevent the decrease in testosterone levels which is thought to be due to dopamine’s ability to inhibit prolactin (a hormone responsible for lowering the levels of luteinizing hormone and testosterone). In addition, mucuna was shown to increase testosterone levels in infertile men from ages 25 to 40. (J Young Pharm. 2011 Apr;3(2):119-24)
Huperzine-A is an alkaloid extracted from club moss (Huperzia Serrata) that has demonstrated both memory enhancement and neuroprotective effects in animal and clinical trials.
Its mechanisms of action are:
Inhibits an enzyme that breaks down acetylcholine: Huperzine-A is a potent, reversible, and specific inhibitor of the enzyme acetylcholinesterase (ACHE), which breaks down acetylcholine. In addition, huperzine A also has other brain-supporting effects that do not involve ACH.
Increases acetylcholine: Huperzine-A increases acetylcholine levels in rat brains for up to 6 hours post-administration. Huperzine-A results in a more prolonged increase in acetylcholine in the whole brain than tacrine, physostigmine, and metrifonate.
Increases norepinephrine and dopamine: Huperzine-A increases levels of norepinephrine and dopamine.
Here are a few of the health benefits of Huperzine-A:
Fig: Huperzine-A suppressed the production of Reactive Oxygen Species on HT22 cells under glutamate stimulation. Cells were treated with 10 μM of HupA for 24 h, followed by treatment of 5 mM glutamate for 12 h. Results were presented as mean ± SD (n = 8). ** p < 0.01 versus control group; ## p < 0.01 versus glutamate-treated group.
Saffron is a spice derived from the flower Crocus sativus and has traditionally been used to flavor food. Saffron contains a host of plant compounds that act as powerful antioxidants and protect cells against free radicals and oxidative stress that can lead to cancer. These compounds are thought to have antidepressant effects, protect brain cells against damage, decrease inflammation, and reduce appetite.
Evidence points to its ability to help improve mood, memory, and protect the brain against oxidative stress. There are some studies that indicate that the antioxidants in saffron tea can help reduce the risk of cardiovascular diseases. Researchers also note that the flavonoids found in saffron also can provide protection.
(Rezaee R, Hosseinzadeh H. Safranal: Iran J Basic Med Sci. 2013;16(1):12-26)
In a double-blind, placebo-controlled study, key ingredients in FOCUSED-AF were shown to decrease reaction time and increase stimulus detection (i.e. higher percentage correct)
During a double-blind, placebo-controlled, randomized study, there was a positive correlation between working memory capacity (on the x-axis: listening span) and influence of key ingredient in FOCUSED-AF (on the y-axis)
During a double-blind, placebo-controlled, randomized study, an ingredient (sulbutiamine=S) in FOCUSED-AF at doses of 12.5 mg/kg (S 12.5) and 25 mg/kg (S 25) greatly increased memory performance (mean; S.E.)
FOCUSED-AF is the ultimate cognitive enhancement supplement, backed by scientific research and formulated with only the highest quality ingredients. Its unique combination of nootropics has been shown to enhance memory, attention, and focus, reduce mental errors, and act as an overall neuroprotective agent.
